Synthetic Heptapeptide
Selank
Anxiolytic Heptapeptide
Selank is a lab-made peptide based on a natural immune compound called tuftsin. It is researched for a calming, anti-anxiety effect that does not appear to cause drowsiness or dependence. In studies it is examined for how it influences BDNF, a protein tied to learning and mood, while supporting steady focus.
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Third-party tested. COA available for this batch (≥99.1% purity).
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Overview
Selank is a synthetic heptapeptide (sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro) studied in academic literature as a tuftsin analog, designed by extending the endogenous immunomodulatory tetrapeptide tuftsin to probe peptide-mediated signaling in neuropharmacology models. Sometimes designated TP-7, this research grade Selank is classified among regulatory peptides examined for activity in the central nervous system. VANTA supplies it strictly as a reference material for in-vitro and preclinical laboratory work, never for human or veterinary use.
The Selank peptide literature describes several mechanistic hypotheses investigated in controlled laboratory systems. One frequently cited line of work examined Selank as an inhibitor of enkephalin-degrading enzymes, reporting in cell-free and plasma assays that the peptide slowed enzymatic hydrolysis of enkephalins. A second body of in-vitro work in neuroblastoma-derived cell lines reported changes in the expression of genes involved in GABAergic neurotransmission. These are associations described in research models, presented here only to characterize the literature.
Investigators have also examined Selank for research across rodent behavioral paradigms and biochemical-marker analyses. Neurotrophic-factor studies in rodents reported that intranasal administration was associated with altered brain-derived neurotrophic factor (BDNF) expression in hippocampal tissue within defined time windows. Each VANTA lot of buy-ready Selank is characterized before release and ships with documentation, so receiving laboratories can reconcile the material against their own analytical references. Findings are reported as observed in their respective systems and do not generalize to human use.
Handling & Reconstitution
In published protocols, Selank is handled as a lyophilized powder reconstituted in an appropriate aqueous solvent for laboratory work, with researchers accounting for peptide solubility, pH, and storage temperature to preserve integrity. Like many short peptides, it is described as sensitive to repeated freeze-thaw cycles and ambient temperature. Store the lyophilized material at -20°C. All handling is intended for trained personnel in controlled research environments.
Frequently asked questions
What is Selank?
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro), sometimes designated TP-7, derived from the immunomodulatory tetrapeptide tuftsin. In the research literature it is described as a tuftsin analog and a tool compound used to probe peptide-mediated signaling in neuropharmacology models for laboratory reference only.
What research areas is Selank studied in?
Preclinical and in-vitro literature examines Selank in the context of enkephalin-degrading enzyme activity, GABAergic neurotransmission gene expression, and BDNF expression in rodent hippocampal tissue. These are associations reported within specific experimental systems, not functional or therapeutic outcomes.
What form and purity is this Selank peptide?
VANTA supplies Selank as a lyophilized powder. Identity is confirmed by mass spectrometry against the expected mass for the heptapeptide sequence, and chromatographic purity is assessed by reversed-phase HPLC, with the purity percentage and chromatogram recorded per lot.
How is research grade Selank stored and reconstituted?
Store the lyophilized powder at -20°C. In published protocols it is reconstituted in an appropriate aqueous solvent, with researchers accounting for solubility, pH, and storage temperature. It is described as sensitive to repeated freeze-thaw cycles and prolonged ambient exposure.
Is Selank third-party tested with a COA?
Every VANTA Selank lot is characterized before release by mass spectrometry for identity and reversed-phase HPLC for purity. These results are compiled into a per-batch Certificate of Analysis (COA) that ships with, or is made available for, the specific lot, letting laboratories verify identity and purity.
Is Selank intended for human use?
No. VANTA provides Selank strictly for laboratory research use only. It is not for human or veterinary use and not for consumption. No diagnostic, therapeutic, or consumption claims are made, and nothing on this page describes use in humans or animals.
Specifications
- Research Class
- Synthetic Heptapeptide
- Form
- Lyophilized Powder
- Storage
- Lyophilized: -20°C.
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use. Must be 21+ to purchase.
