Tetrapeptide
Epitalon
Telomerase Tetrapeptide
Epitalon, also called Epithalon, is a lab-made peptide based on a substance the pineal gland produces naturally. It is researched for how the body manages aging at the cellular level, including telomere length and the daily sleep-wake clock. In studies it is examined for switching on telomerase, an enzyme tied to how long cells stay healthy.
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Overview
Epitalon, also written Epithalon, is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG), derived from the amino-acid composition of the pineal preparation Epithalamin. In the peptide-bioregulation and gerontology literature it is described as a short regulatory peptide and has been examined across in-vitro, in-vivo, and in-silico research models. VANTA supplies this epitalon peptide strictly as a reference-grade material for laboratory research, not as a drug, supplement, or article for human use.
Preclinical literature has studied the AEDG tetrapeptide in a range of experimental contexts, including cell-culture models, rodent-aging models, and molecular-modeling approaches. Reported observations are described as model-specific and are not extrapolated to humans. Research areas referenced for this peptide class include telomere and cellular-aging models, gene-expression and epigenetic hypotheses, and circadian and antioxidant processes, each studied only within defined experimental systems.
Researchers selecting research grade epitalon prioritize a characterized, traceable test article. Each VANTA lot is assessed by reversed-phase HPLC for chromatographic purity and confirmed by mass spectrometry for identity against the expected AEDG tetrapeptide mass. A per-batch Certificate of Analysis accompanies each lot, so every experiment can be tied to a specific, documented batch and its underlying analytical data.
Research Areas
Handling & Reconstitution
Epitalon ships as a lyophilized powder for laboratory reconstitution. The sealed lyophilized vial is stored at -20C and protected from light. Researchers reconstitute with an appropriate solvent immediately before experimental use, following their own institutional protocols, and keep reconstituted material refrigerated. These are general reference points for laboratory handling, not instructions for any in-vivo application.
Frequently asked questions
What is Epitalon?
Epitalon, also written Epithalon, is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG), derived from the amino-acid composition of the pineal preparation Epithalamin. The literature describes it as a short regulatory peptide examined in cellular-aging, telomere, and circadian research models. VANTA supplies it for laboratory research only.
What form and purity is the VANTA epitalon peptide supplied in?
It is supplied as a lyophilized powder. Each lot is assessed by reversed-phase HPLC to quantify chromatographic purity and confirmed by mass spectrometry against the expected AEDG tetrapeptide mass, so researchers can attribute results to the peptide rather than to impurities.
How is research grade epitalon stored and reconstituted?
The sealed lyophilized vial is stored at -20C and protected from light. Researchers reconstitute with an appropriate solvent immediately before experimental use per their own institutional protocols, then keep the reconstituted solution refrigerated. These are handling reference points, not usage directions.
Does each batch include a COA?
Yes. Every batch ships with a per-batch Certificate of Analysis documenting the HPLC purity result and the mass-spectrometry identity confirmation for that specific lot. This per-lot documentation lets a laboratory tie each experiment to a traceable batch and its underlying analytical data.
What research areas has Epitalon been studied in?
Framed for research context, the AEDG tetrapeptide has been examined in models related to cellular aging and telomere biology, gene-expression and epigenetic hypotheses, and circadian and antioxidant processes. These are model-specific research areas, not established outcomes in humans.
Is Epitalon intended for human use?
No. Epitalon is supplied strictly for in-vitro and laboratory research use by qualified professionals. It is not a drug, supplement, food, or cosmetic and is not intended for human or veterinary consumption, administration, diagnosis, or treatment of any kind.
Specifications
- Research Class
- Tetrapeptide
- Sequence
- Ala-Glu-Asp-Gly
- Molecular Formula
- C14H22N4O9
- Molar Mass
- 390.35 g/mol
- Form
- Lyophilized Powder
- Storage
- Lyophilized: -20°C.
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use. Must be 21+ to purchase.
